A model of the early flowering signal pathway in 45OX transgenic rice. The ectopic expression of OsMADS45 activates the upstream genes Hd3a and RFT1 at early developmental stages and upregulates the expression of OsMADS14 and OsMADS18 either via the upregulated of Hd3a and RFT1 or direct induction via the constitutive expression of OsMADS45. The expression of OsMADS45 represses the expression of Hd1 at early developmental stages. The increased expression of the OsMADS14 and OsMADS18 genes caused early flowering in 45OX transgenic rice. However, the ectopic expression of OsMADS45 does not alter the expression of OsMADS50, Ehd1, Ehd2/OsId1/RID1 and OsGI.