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Table 2 Effect of fungal elicitors on andrographolide production (Mean ± SD)

From: Enhanced synthesis of andrographolide by Aspergillus niger and Penicillium expansum elicitors in cell suspension culture of Andrographis paniculata (Burm. f.) Nees

Name of elicitors

Treatment durations

Concentrations of elicitor

Andrographolide content in μg/g

Fold increase

  

Control

21.0 ± 0.74

 

Aspergillus niger

4 days

1.0 ml

52.0 ± 0.13

2.47

1.5 ml

45.0 ± 0.61

2.14

2.0 ml

19.0 ± 0.3

-

 

Control

88.0 ± 0.37

 

7 days

1.0 ml

331.0 ± 0.43

3.76

1.5 ml

88.0 ± 0.34

-

2.0 ml

8.0 ± 0.70

-

 

Control

19.0 ± 0.13

 

10 days

1.0 ml

42.0 ± 0.94

2.21

1.5 ml

132.0 ± 0.62

6.94

2.0 ml

47.0 ± 0.74

2.47

  

Control

10.0 ± 0.11

 

Penicillium expansum

2 days

0.3%

12.0 ± 0.84

1.2

0.6%

22.0 ± 0.83

2.2

1.2%

16.0 ± 0.69

1.6

 

Cont.

24.0 ± 0.28

 

5 days

0.3%

22.0 ± 0.86

-

0.6%

35.0 ± 0.95

1.45

1.2%

32.0 ± 0.11

1.33

 

Cont.

13.0 ± 0.45

 

8 days

0.3%

29.0 ± 0.14

2.23

0.6%

81.0 ± 0.74

6.23

  

1.2%

15.0 ± 0.21

1.15