Folium Sennae protects against hydroxyl radical-induced DNA damage via antioxidant mechanism: an in vitro study

Botanical Studies

Table 1 The R (correlation coefficient) values between chemical contents and antioxidant levels (1/IC ₅₀ value)

	Total phenolics	Total sugars	Total saponins	Total anthraquinones	Aloe-emodin	Rhein	Emodin
Protection against DNA damage	0.769	0.330	−0.589	0.747	0.773	0.753	0.662
•OH scavenging	0.814	0.561	−0.571	0.650	0.326	0.650	0.575
•O₂^– scavenging	0.865	0.182	0.328	0.743	0.674	0.719	0.664
DPPH• scavenging	0.91	−0.112	0.155	0.997	0.922	0.994	0.983
ABTS⁺• scavenging	0.918	−0.036	0.158	0.962	0.872	0.958	0.931
Cu²⁺-reducing	0.784	−0.306	0.56	0.896	0.952	0.884	0.886
Average	0.843	0.103	0.0068	0.833	0.753	0.820	0.784