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Botanical Studies
Figure 1 | Botanical Studies

Figure 1

From: Vasorelaxing and antihypertensive activities of synthesized peptides derived from computer-aided simulation of pepsin hydrolysis of yam dioscorin

Figure 1

ACE inhibition by 23 synthesized peptides (40 μM) derived from a computer-aided simulation of pepsin hydrolysis of yam dioscorin. The 0.1% DMSO solution was used instead of sample solution for blank experiments (ΔAblank/min). The decreased absorbance at 345 nm (ΔAsample/min) was recorded during 90 sec at room temperature. The ACE inhibition (%) was calculated as followed: [1 - (ΔAsample/min ÷ ΔAblank/min)] × 100. The synthesized peptides included (1) KTCGNGME, (2) PPCSE, (3) CDDRVIRTPLT, (4) KTCGY, (5) PPCTE, (6) RDNGVIF, (7) KRIHF, (8) RRDY, (9) RSVF, (10) PTNF, (11) GISW, (12) MGSF, (13) VSIL, (14) HSPA, (15) DPF, (16) RY, (17) RF, (18) NW, (19) RL, (20) GVI, (21) GSL, (22) SY, and (23) GPA. Arrow indicated peptide with ACE inhibition over 50%.

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