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Botanical Studies
Fig. 5 | Botanical Studies

Fig. 5

From: Actinidia callosa var. callosa suppresses metastatic potential of human hepatoma cell SK-Hep1 by inhibiting matrix metalloproteinase-2 through PI3K/Akt and MAPK signaling pathways

Fig. 5

Inhibitory effect of EAAC on MAPK (a), and PI3K, AKT (b) signaling pathway. SK-Hep1 cells were cultured in serum-free media containing 0, 50, 100, 150, and 200 mg/mL EAAC for 24 h, and the cell lysates were subjected to SDS-PAGE followed by western blotting. Activities of these proteins were subsequently quantified by densitometric analyses, with the control set to 100%. The data were presented as mean ± SD for three different experiments performed in triplicate. *p < 0.05, **p < 0.01 and ***p < 0.001 were compared with untreated control group

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