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Botanical Studies

Table 2 Cytotoxicity of the ethanolic extract of the F. rugosa VOG 127 sample using the MTT method

From: First report of chemical composition and cytotoxicity evaluation of Foraminispora rugosa basidiomata from Brazil

Cell lines

IC50*(µg/mL) values

VOG 127

Doxorrubicin

MV3

151.3 ± 19.3

3.83 ± 1.5

MIAPaCa-2

154.9 ± 9.1

23.53 ± 2.3

SH-Sy5y

216.7 (n = 1)

5 .00 ± 0.0#

C6

213.6 ± 11.8

1.31 ± 0.4##

HepG2

138.5 ± 3.2

1.5 ± 0.6

L929

153.6 ± 7.6

7.83 ± 0.8

Vero

119.5 ± 2.2

82.4 ± 8.7

  1. *The activity was shown as the IC50 value, which was the concentration of the tested ethanolic extract (µg/mL) that decreased the number of viable cells by 50%. Results are expressed as the mean and standard error values of triplicate data points. Cell lines: MV3: human melanoma; MIAPaCa-2: human pancreas carcinoma; SH-Sy5y: human neuroblastoma; C-6: astroglial C6 cells; HEp-G2: human hepatoblastoma; L929: non-transformed mammalian fibroblast; Vero: mammalian kidney epithelial. Literature data: #Namkaew et al. (2018). ##Zhao et al. (2016)
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