Botanical Studies

Table 3 IC₅₀ values of 5, 11, and 12 on nitric oxide production inhibitory activities induced by lipopolysaccharide in microglial BV-2 cells

From: Chemical constituents from the medicinal herb-derived fungus Chaetomium globosum Km1226

compound	IC₅₀ (µM) ^a,b
5	0.7 ± 0.1***
11	1.2 ± 0.1**
12	1.6 ± 0.2**
Curcumin ^c	2.7 ± 0.3

**p < 0.01
***p < 0.001
^aIC₅₀ = concentration that reduces NO production by 50%
^bAsterisks denote significance compared to curcumin (positive control) according to the two-tailed t-test
^cPositive control used in this study

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