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Table 4 Anti-angiogenic activity of isolated compounds in human EPCs

From: Chemical constituents from the medicinal herb-derived fungus Chaetomium globosum Km1226

compound

IC50 (µM) a

1

> 50

2

> 50

3

> 50

4

> 50

5

5.6 ± 0.1

6

> 50

7

> 50

8

4.6 ± 0.1

9

8.1 ± 0.4

10

0.8 ± 0.3

11

5.2 ± 0.3

12

2.9 ± 0.3

13

> 50

14

> 50

Sorafenib b

4.8 ± 0.3

  1. aEPCs were treated with the indicated compounds for 48 h. Anti-angiogenic effects were evaluated in a cell growth assay (n = 3). Data are displayed as the mean ± SEM
  2. bPositive control used in this study