Fig. 4

Effect of dragon blood crude extracts on the fasting blood glucose level in C57BL/6JNarl male mice model, (A) body weight, (B) fasting blood glucose levels, and (C) violin plot. (A) The weekly body weight of the C57BL/6JNarl male mice orally administered dragon blood crude extract suspension (DB) and control solution for ten weeks. The body weight of male B6 mice showed a steady increase during the experimental period, with no significant weight differences observed between the experimental (N = 8) and control groups (N = 8) from Week 0 to Week 10. (B) Fasting blood glucose of the C57BL/6JNarl male mice orally administered with dragon blood crude extract suspension solution compared to the control solution over ten weeks. At seven weeks of age (Week 0), animals were randomly assigned to either the dragon blood crude extract-treated (DB) or the control group and were trained to be accustomed to handling and restraining. The control and the experimental groups showed significant differences at weeks 0, 2, 5, 7, 8, 9, and 10. (C) The violin plot of fasting blood glucose is significantly lower in the BD-treated group than in the control group. The fasting glucose from the DB and the control group from W1 to W5 and form W7 to W10 (W6 data removed). The data were expressed as mean SD (N = 8). Dragon blood crude extract-treated group (Mean ± SD = 165.35 ± 24.60), and control group (Mean ± SD = 182.78 ± 24.81) with p-value = 1.541 × 10^− 5